People with two copies of the E4 allele (ApoE4/4) have a ~65% chance of developing Alzheimer's disease (AD) by age 85, compared to only 10% in people with both wild-type E3 alleles. This remarkable ...

Neurospheres—the colloquial name for a common and long-noted tissue-culture phenomenon—represent three-dimensional floating spheroid cell clusters that form in vitro when mitotic cells from the ...

Neural organoids and 3D spheroids are a fast-evolving technology with enormous potential for studying brain development and neuronal disorders. They offer a more sophisticated and physiologically ...