The DNA damage from ionizing radiation (IR) erupting from the Chernobyl nuclear disaster of 1986 is showing up in the ...
A reanalysis of whole-genome data from 130 children conceived after the Chernobyl disaster has identified a statistically ...
They found an average of 2.65 clustered de novo mutations (cDNMs) per child, compared to 0.88 cDNMs in children of unexposed ...
It took a while for the science to basically catch up to that suspicion.” In these types of “recessive” conditions, the ...
Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...
Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth. By testing every possible mutation in a critical hotspot, they found that ...