This article and associated images are based on a poster originally authored by William LaMarr, Dave Garby, Jeremiah Bowers, Lisa Boatner, Somayeh Talebzadeh, Aaron Wolfe, Sekar Ramachandran, and ...

A research team has developed an innovative technique that enables precise modification of specific proteins within complex biological environments. A research team led by Professor Seung Soo Oh and ...

The newly launched Hyku Biosciences provides a platform for covalent drug development which may be a better approach for treating diseases like cancer. One of Hsu's SuTEx molecules targets sites on ...

Covant Therapeutics, Roivant’s latest spin-off company, will have a major partner with whom to explore the benefits of covalency, courtesy of an exclusive research pact and licensing deal with ...

Proteins are important molecules—but they aren’t the only molecules in a cell, and they don’t operate alone. In a new preprint, the team behind the protein structure prediction software RoseTTAFold ...

Allyl isothiocyanate, the pungent principle of wasabi and other mustard oils, produces pain by activating TRPA1, an excitatory ion channel on sensory nerve endings. Isothiocyanates are ...

Researchers at Baylor College of Medicine have developed a powerful new data analysis method named COOKIE-Pro (Covalent Occupancy Kinetic Enrichment via Proteomics) that provides a comprehensive, ...

A new high-throughput study that used publicly available data shows that E. coli proteins containing a structure called a non-covalent lasso entanglement (NCLE) are more likely to misfold and, if they ...